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KMID : 1172020150160020017
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Journal of Korean Bioethics Association
2015 Volume.16 No. 2 p.17 ~ p.29
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Ethical Issues on the Human Embryonic Genome Editing
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Jun Bang-Ook
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Abstract
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The advance of nucleases technology in the past decade has enabled researchers to edit the genomes of various types of cells and organisms. Newly developed clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9(CRISPR associated 9) system is much easier to handle and thus is being used in many laboratories worldwide instead of conventional genetic engineering technique. A series of papers on mammalian embryos and human embryonic stem cells edited by CRISPR/Cas9 system has been published, which has evoked concerns that the editing of human embryo genome is very near. While groups of scientists insisted to call for a moratorium, Chinese scientists published world first paper on the editing of the human embryo genome in April this year, which generated fierce debate. Therefore, this paper will consider ethical implication of the genome editing experiment already done on the human embryo, and will suggest that the immediate response of bioethics community is required to establish the ethics of human embryo genome editing.
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KEYWORD
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Human Germline Editing, Human Embryo Genome Editing, Bioethics
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